Template activity in liver DNA from rats fed with malondialdehyde
نویسندگان
چکیده
منابع مشابه
Glyoxalase Activity of Liver from Rats Fed #-Dimethylaminoazobenzene*
Reduced glutathione (GSH) is required as coenzyme (12). Since Reaction A is catalyzed at a rate that, within certain limits, is independent of the substrate concentration (18), it belongs to the class of "zero order" reactions, of which the succinoxidase system is a type. Glyoxalase is found in practically all tissues, and in the case of animal tissues it is present in especially high concentra...
متن کاملMicrofluorometric determination of DNA adducts in immunofluorescent-stained liver tissue from rats fed 2-acetylaminofluorene.
The intensities of immunofluorescence in nuclei stained by an antiserum specific for the DNA adduct N-deoxyguanosin(8-yl)aminofluorene (dG-8-AF), were quantified by microfluorometry in frozen liver sections from male Fischer rats fed 2-acetylaminofluorene (AAF). Results of previous studies demonstrated that dG-8-AF is the predominant adduct (80-100%) formed in livers of rats fed AAF continuousl...
متن کاملFatty acid synthetase activity in the liver and adipose tissue of rats fed with various carbohydrates.
1. The inclusion of sucrose in the diet of rats led to an increase in hepatic fatty acid synthetase activity compared with that of rats fed with starch as the sole carbohydrate. The higher activity occurred within 18h of the introduction of sucrose and persisted with fluctuations for the 30 days of the experiment. Reversal of the diets in some rats after 21 days led to changes in the enzyme act...
متن کاملAnti-oxidant and anti-hyperlipidemic activity of Hemidesmus indicus in rats fed with high-fat diet
Objective: Dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. The present study was designed to investigate the ameliorative potential of different extracts of Hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action. Materials and Methods: Male wistar rats were divided into 6...
متن کاملMalondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload.
In hepatic iron overload, iron-catalyzed lipid peroxidation has been implicated in the mechanisms of hepatocellular injury. Lipid peroxidation may produce reactive aldehydes such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which may form aldehyde-protein adducts. We investigated whether lipid peroxidation occurred in rats fed a diet containing 3% carbonyl iron for 5-13 wk, and if thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Letters
سال: 1969
ISSN: 0014-5793
DOI: 10.1016/0014-5793(69)80136-5